Today, for my science solution, I will be explaining the difference between a A prokaryotic cell does not have a nucleus or any organelles. It is a primitive and is common in bacteria. Prokaryotes also have ribosomes and are about one tenth of the size of a eukaryotic cell. A eukaryotic cell has a nucleus and organelles. They are much more advanced than prokaryotic cells and are found in plants and animals. THey are about ten times the size of a prokaryote. These are the main differences